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Causes of Generic Drug Shortages: Manufacturing and Supply Chain Vulnerabilities

Causes of Generic Drug Shortages: Manufacturing and Supply Chain Vulnerabilities

Caspian Mortensen Jan, 28 2026 15

Generic drug shortages are caused by fragile manufacturing systems, global supply chain dependencies, and unsustainable pricing. With 95% of shortages involving generics, the U.S. system lacks backup capacity, transparency, and incentives to produce low-margin but essential medicines.

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